Document Detail


Angiographic and clinical characteristics of patients with unstable angina showing an ECG pattern indicating critical narrowing of the proximal LAD coronary artery.
MedLine Citation:
PMID:  2784024     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred eighty of 1260 patients consecutively admitted to the hospital because of unstable angina pectoris had the typical ST-T segment changes suggestive of a critical stenosis in the proximal LAD. In 108 patients the ECG abnormalities were present at the time of admission. In the remaining 72 patients they developed shortly thereafter. The difference between these two groups was a longer duration of anginal complaints in the former (mean 2.3 days). Results of coronary angiography, performed a mean of 4.6 days after the last attack of chest pain, showed 50% or more narrowing in the proximal LAD in all patients. Thirty-three patients had complete occlusion of the LAD and 75 had collateral circulation to the LAD. Results of left ventricular angiography showed abnormal systolic left ventricular wall motion in 137 patients and normal systolic motion in the remaining 43 patients. The difference between these two groups was a shorter mean time interval between the last attack of chest pain and angiography in the former group (p less than 0.001). Twenty-four patients had only abnormal diastolic wall motion. Twenty-one patients had a small increase in the creatine kinase level at the time of admission. Fifteen patients (nine before and six during early revascularization) had an anterior wall myocardial infarction in the hospital; these patients had a patent but severely narrowed LAD and a low incidence of collateral circulation to the LAD.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
C de Zwaan; F W Bär; J H Janssen; E C Cheriex; W R Dassen; P Brugada; O C Penn; H J Wellens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  117     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-04-04     Completed Date:  1989-04-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  657-65     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiology, University of Limburg, Academic Hospital Maastricht, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Angina Pectoris / diagnosis*
Angina, Unstable / diagnosis*,  surgery
Arrhythmias, Cardiac / diagnosis
Aspartate Aminotransferases / blood
Coronary Angiography*
Coronary Artery Bypass
Coronary Disease / diagnosis*
Electrocardiography*
Female
Follow-Up Studies
Heart Catheterization
Heart Ventricles / radiography*
Humans
Male
Middle Aged
Myocardial Contraction
Myocardial Infarction / diagnosis,  surgery
Postoperative Complications / mortality
Prognosis
Chemical
Reg. No./Substance:
EC 2.6.1.1/Aspartate Aminotransferases

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