Document Detail

Angiographic changes (Dotter effect) produced by intravascular ultrasound imaging before coronary angioplasty.
MedLine Citation:
PMID:  8037089     Owner:  NLM     Status:  MEDLINE    
Intravascular ultrasound (IVUS) imaging of the coronary arteries has recently been introduced for the study of coronary lesions, but the angiographic effects produced by an IVUS examination before coronary angioplasty are unknown. Accordingly, the feasibility of and the potential angiographic changes caused by IVUS study (4.8F catheter) of severe coronary lesions was prospectively studied. Thirty consecutive coronary lesions were analyzed before intervention (29 patients, mean age 61 +/- 9 years, 5 women and 24 men). Before and after IVUS examination, intracoronary nitroglycerin 0.2 mg, was administered and two orthogonal angiographic views obtained. In 17 (57%) lesions the transducer of the IVUS catheter (radiopaque) could be gently advanced for precise location at the lesion site, and in every case the ultrasonic images revealed that the catheter was wedged into the plaque. In the remaining 13 lesions only the catheter tip but not the transducer could be located at the lesion site. Baseline minimal luminal diameter was similar in the crossed lesions and in lesions that prevented complete advancement of the IVUS catheter (0.86 +/- 0.2 vs 0.82 +/- 0.2 mm, difference not significant). Lesion characteristics could not predict the feasibility of the IVUS study. No complications resulted from the IVUS study. Quantitative angiography (automatic edge-detection system) revealed a significant increment in minimal luminal diameter (0.84 +/- 0.2 vs 1.16 +/- 0.3 mm, p < 0.001) and minimal luminal cross-sectional area (0.67 +/- 0.4 vs 1.09 +/- 0.5 mm2, p < 0.01) after passage of the IVUS catheter.(ABSTRACT TRUNCATED AT 250 WORDS)
F Alfonso; C Macaya; J Goicolea; R Hernandez; C Bañuelos; A Iñiguez; J Zamorano; P Zarco
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American heart journal     Volume:  128     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-08-18     Completed Date:  1994-08-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  244-51     Citation Subset:  AIM; IM    
Cardiopulmonary Department, Hospital Universitario San Carlos, Madrid, Spain.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary
Coronary Angiography*
Coronary Disease / radiography,  therapy,  ultrasonography*
Coronary Vessels / ultrasonography*
Feasibility Studies
Middle Aged
Prospective Studies
Ultrasonography, Interventional*

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