Document Detail

Angiographic and artefact-free computed tomography imaging of experimental aneurysms embolised with hydrogel filaments.
MedLine Citation:
PMID:  19763579     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: We compared experimental rabbit carotid bifurcation aneurysms embolised with platinum coils or hydrogel filaments by using digital subtraction angiography (DSA) and computed tomography angiography (CTA). METHODS: Embolisation was performed using platinum coils (n = 2), hydrogel filaments loaded with iodine (n = 3) and hydrogel filaments loaded with barium sulphate (n = 3). In one case, a stent was deployed in the parent vessel to determine the effect of hydrogel filaments on stent visualisation. DSA evaluations occurred immediately post-treatment. CTA evaluations occurred at 0-13 weeks post-treatment. The DSA and CTA images were evaluated for the lack of artefacts and the visibilities of the embolic mass, individual coils and residual flow in the aneurysm sac and neck. RESULTS: The DSA results were largely concordant among the three groups. The embolic masses were readily evident with some individual coils being distinguished. In the aneurysms embolised with hydrogel filaments, visualisation of the individual coils, residual flow and stent with minor or no artefacts was possible using CTA. On the other hand, the beam hardening artefacts precluded analysis of aneurysms embolised with platinum coils. CONCLUSION: CTA-compatible embolic devices could have wide applications in diverse locations throughout the vasculature, particularly in combination with stents or stent grafts.
Mark R McCoy; Gregory M Cruise; Monika Killer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-09-16
Journal Detail:
Title:  European radiology     Volume:  20     ISSN:  1432-1084     ISO Abbreviation:  Eur Radiol     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-10     Completed Date:  2010-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  870-6     Citation Subset:  IM    
Department of Radiology and Magnetic Resonance Tomography, Christian Doppler Clinic, Paracelsus Medical University, Salzburg, Austria.
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MeSH Terms
Aneurysm / radiography*,  therapy*
Angiography, Digital Subtraction / instrumentation*
Embolization, Therapeutic / instrumentation*,  methods
Radiographic Image Enhancement / methods*
Tomography, X-Ray Computed / instrumentation*,  methods
Treatment Outcome
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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