| An Angiographic Predictor of Pulmonary Artery Stenosis After the Norwood-Sano Operation for Hypoplastic Left Heart Syndrome. | |
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MedLine Citation:
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PMID: 22447359 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The objective of this study was to determine angiographic predictors of future pulmonary artery stenosis (PS) in patients with hypoplastic left heart syndrome (HLHS) at the time of pre-stage 2 cardiac catheterization (PS2C). The Sano modification of the Norwood operation (NSO) for HLHS includes placement of a right ventricle-to-pulmonary artery (RV-PA) conduit. Branch PS is a recognized complication. Data from patients with HLHS who underwent NSO from 2005 to 2009 and who underwent PS2C were reviewed retrospectively. Nakata and McGoon indices were calculated in the traditional fashion, and modified Nakata and McGoon indices were calculated using the narrowest branch PA diameters. Thirty-three patients underwent NSO and 28 patients underwent PS2C. Mean follow-up was 35.8 ± 7.5 months. Ten (36 %) patients had significant left branch PS, with two requiring balloon angioplasty and eight requiring stent placement, a median of 15.2 months after PS2C (interquartile range 1.2, 32.8). The modified Nakata index was predictive of future intervention for left PS (receiver operating characteristic curve area under the curve 0.811), with a cut-off of 135 mm(2)/m(2) and a sensitivity of 100 % and specificity of 72.2 %. A modified Nakata index <135 mm(2)/m(2) at PS2C predicts future need for intervention on left-branch PS in patients with HLHS after the NSO. Surgical pulmonary arterioplasty at the time of stage 2 surgical palliation may obviate the need for future interventions. |
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Authors:
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Michael D Seckeler; Carlos M Mery; James J Gangemi; Benjamin B Peeler; K Anitha Jayakumar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-24 |
Journal Detail:
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Title: Pediatric cardiology Volume: - ISSN: 1432-1971 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8003849 Medline TA: Pediatr Cardiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Division of Pediatric Cardiology, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USA, ms3ec@hscmail.mcc.virginia.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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