Document Detail

Angiogenic imbalances: the obstetric perspective.
MedLine Citation:
PMID:  20231008     Owner:  NLM     Status:  MEDLINE    
Clinical and experimental evidence indicates that angiogenic imbalances may participate in the mechanisms of disease of several pregnancy complications, some of which may be life threatening. This article reviews current evidence in support of this view and the possibility that the fetus may play a central role in these imbalances; it also reviews recent experimental observations that modulation of angiogenic imbalances during pregnancy may have prophylactic and/or therapeutic value.
Jimmy Espinoza; John E Uckele; Robert A Starr; David E Seubert; Andres F Espinoza; Stanley M Berry
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-03-15
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  203     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-08     Completed Date:  2010-09-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  17.e1-8     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 Mosby, Inc. All rights reserved.
Department of Obstetrics and Gynecology, William Beaumont Hospital, 3601 West Thirteen Mile Rd., Royal Oak, MI 48073, USA.
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MeSH Terms
Fetal Growth Retardation / physiopathology
Hydatidiform Mole / physiopathology
Neovascularization, Pathologic / physiopathology*
Ovarian Hyperstimulation Syndrome / physiopathology
Pre-Eclampsia / physiopathology
Pregnancy Complications / physiopathology*
Vascular Endothelial Growth Factor A / physiology
Reg. No./Substance:
0/VEGFA protein, human; 0/Vascular Endothelial Growth Factor A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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