| Angiogenic Factors and Pregnant Woman with New Onset Seizures. | |
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MedLine Citation:
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PMID: 22380455 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background. In patients with new onset seizures during pregnancy, it can be challenging to differentiate between eclampsia and other etiologies. Soluble fms-like tyrosine kinase (sFlt1) is an antiangiogenic protein that is elevated in preeclampsia and eclampsia. Case. A multiparous woman presented at 22 weeks gestation with seizures. The initial presentation was highly suspicious for eclampsia, but blood pressure and laboratory data were equivocal. Further investigation suggested primary seizure disorder. Serum sFlt1 was normal for gestational age, supporting the exclusion of eclampsia. Conclusion. History, physical exam, and traditional laboratory data are the mainstays of eclampsia diagnosis; however, sFlt1 may help clinicians when the diagnosis is uncertain at preterm gestational ages. |
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Authors:
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Hayley Quant; Deborah Arden; Tamara Takoudes; Sarosh Rana |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-1 |
Journal Detail:
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Title: Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy Volume: - ISSN: 1525-6065 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9421297 Medline TA: Hypertens Pregnancy Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA , USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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