| Angiogenesis inhibitors in the treatment of small cell and non-small cell lung cancer. | |
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MedLine Citation:
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PMID: 15474338 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Angiogenesis is believed to play a critical role in cancer; however, antiangiogenic therapy has not been demonstrated to improve the survival of patients who have lung cancer. In this article, the evidence that supports a role for angiogenesis in the pathogenesis of lung cancer, trials of antiangiogenic agents in lung cancer performed to date, and the lessons learned from these studies are discussed. |
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Authors:
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Fiona H Blackhall; Frances A Shepherd |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Hematology/oncology clinics of North America Volume: 18 ISSN: 0889-8588 ISO Abbreviation: Hematol. Oncol. Clin. North Am. Publication Date: 2004 Oct |
Date Detail:
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Created Date: 2004-10-11 Completed Date: 2004-12-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8709473 Medline TA: Hematol Oncol Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 1121-41, ix Citation Subset: IM |
Affiliation:
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Department of Medical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Manchester, M20 4BX England, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Angiogenesis Inhibitors
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therapeutic use* Carcinoma, Non-Small-Cell Lung / blood supply, drug therapy* Carcinoma, Small Cell / blood supply, drug therapy* Clinical Trials as Topic Humans Lung Neoplasms / blood supply, drug therapy* Neovascularization, Pathologic / prevention & control Protease Inhibitors / therapeutic use Vascular Endothelial Growth Factor A / antagonists & inhibitors |
| Chemical | |
Reg. No./Substance:
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0/Angiogenesis Inhibitors; 0/Protease Inhibitors; 0/Vascular Endothelial Growth Factor A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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