Document Detail

Angiofollicular and plasmacytic polyadenopathy: a pseudotumourous syndrome with dysimmunity.
MedLine Citation:
PMID:  7440754     Owner:  NLM     Status:  MEDLINE    
Two cases are reported of an apparently distinct type of immune disorder. Beginning with mild anaemia and widespread massive lymphadenopathy, the disease progressed to a fatal autoimmune type haemolytic anaemia. Serum investigation showed polyclonal hypergamma-globulinaemia and some autoantibodies. Repeat lymph node biopsies in each case showed hyperplasia within B lymphocyte territory (follicular hyperplasia and polyclonal plasmacytosis with IgG predominance) and atrophy of T dependent areas. Dilatation of lymph sinuses, vascular proliferation, and sclerosis were striking features. This appears to be a new entity, and reasons are given for separating this disease from other pseudotumourous lymph node disorders associated with dysimmunity.
J Diebold; M Tulliez; A Bernadou; J Audouin; G Tricot; M Reynes; G Bilski-Pasquier
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  33     ISSN:  0021-9746     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-02-19     Completed Date:  1981-02-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1068-76     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia, Hemolytic, Autoimmune / complications*,  immunology,  pathology
Hypergammaglobulinemia / complications*,  immunology,  pathology
Immunoglobulin G / analysis*
Lymph Nodes / immunology,  pathology
Lymphatic Diseases / complications*,  immunology,  pathology
Reg. No./Substance:
0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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