Document Detail

Angiofollicular lymph node hyperplasia and peripheral neuropathy. Case report and literature review.
MedLine Citation:
PMID:  1849398     Owner:  NLM     Status:  MEDLINE    
A man with multicentric angiofollicular lymph node hyperplasia and a polyclonal gammopathy developed a debilitating sensory-motor peripheral neuropathy that resolved with plasma-pheresis and immunosuppressive therapy. Fourteen similar cases have been reported in the literature; however, to our knowledge, this is the first report of successful treatment with plasma-pheresis. Severe peripheral neuropathy usually occurs in the setting of multicentric, plasma cell-type disease with hypergammaglobulinemia and is often responsive to immunosuppressive therapy.
B Scherokman; S J Vukelja; E May
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Archives of internal medicine     Volume:  151     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1991 Apr 
Date Detail:
Created Date:  1991-05-07     Completed Date:  1991-05-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  789-90     Citation Subset:  AIM; IM    
Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, Md. 20889.
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MeSH Terms
Azathioprine / therapeutic use
Giant Lymph Node Hyperplasia / complications*
Peripheral Nervous System Diseases / complications*,  therapy
Prednisone / therapeutic use
Reg. No./Substance:
446-86-6/Azathioprine; 53-03-2/Prednisone

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