Document Detail


Angiocentric glioma: a case report and review of the literature.
MedLine Citation:
PMID:  19941376     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Angiocentric glioma (AG) is a rare central nervous system (CNS) neoplasm that was only recently recognized by the World Health Organization (WHO). AG occurs in a broad age range, shows no gender predilection, and arises superficially in the cerebrum, usually resulting in medically intractable seizures. Most cases are cured by surgical excision alone, consistent with a WHO grade I neoplasm. We report a case of an AG in the right frontal lobe of a 57-year-old female, emphasizing the cytologic and immunohistochemical features, including confirmation and comparison with the surgical specimen. To our knowledge, this is the first report detailing the cytology of AG, including demonstration of important diagnostic findings that were only appreciated in the cytologic preparations and not in the smears or the surgical specimen. We also compare and contrast AG to other entities in the differential diagnosis and include a review of the literature.
Authors:
Ryan T Mott; Thomas L Ellis; Kim R Geisinger
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  38     ISSN:  1097-0339     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-17     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  452-6     Citation Subset:  IM    
Copyright Information:
(c) 2009 Wiley-Liss, Inc.
Affiliation:
Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. rmott@wfubmc.edu
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MeSH Terms
Descriptor/Qualifier:
Brain Neoplasms / metabolism,  pathology*,  radiotherapy
Diagnosis, Differential
Dose Fractionation
Ependymoma / pathology
Female
Frontal Lobe / pathology
Glioma / metabolism,  pathology*,  radiotherapy
Humans
Immunohistochemistry
Middle Aged
Migraine Disorders / complications
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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