Document Detail


Angio-immunoblastic lymphadenopathy. A report of 3 cases.
MedLine Citation:
PMID:  1273737     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Angio-immunoblastic lymphadenopathy (AILD) was diagnosed in 3 Black patients, AILD is a non-malignant disorder which resembles a malignant lymphoma clinically and morphologically. It is thought to represent an abnormal response of B lymphocytes to antigenic stimuli which are often therapeutic agents. The disorder usually affects adults of the older age group and the clinical course can be rapidly fatal, particularly if vigorous chemotherapy is given. Of the 3 patients with AILD, 2 died from complicating infections within 6 months after the initial diagnosis. The third patient was completely cured after short courses of prednisone and vincristine. It appears that in some patients the disorder may be completely reversible but whether these patients are at a greater risk of eventually developing a lymphoma is uncertain at the present time, and remains to be ascertained by their long-term follow-up.
Authors:
R J Jacobson; A Schmaman; J E Morley; B Golding; J J Rippey
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde     Volume:  50     ISSN:  0256-9574     ISO Abbreviation:  S. Afr. Med. J.     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2014-09-12    
Medline Journal Info:
Nlm Unique ID:  0404520     Medline TA:  S Afr Med J     Country:  SOUTH AFRICA    
Other Details:
Languages:  eng     Pagination:  707-10     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Antineoplastic Agents / therapeutic use
Female
Humans
Lymph Nodes* / pathology
Lymphatic Diseases* / drug therapy,  pathology
Male
Prednisone / therapeutic use
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; VB0R961HZT/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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