Document Detail

Angina pectoris with normal coronary arteries in Shy-Drager syndrome.
MedLine Citation:
PMID:  512666     Owner:  NLM     Status:  MEDLINE    
A patient with Shy-Drager syndrome who presented with severe angina pectoris is described. Special investigations of his autonomic nervous system showed sympathetic and parasympathetic dysfunction with supersensitive end-organ response. Sympathetic dysfunction manifested as labile hypertension, severe postural hypotension, and inadequate heart rate response to atropine and the Valsalva manoeuvre. These changes in blood pressure were accompanied by severe disabling angina pectoris. Selective coronary angiography showed normal coronary arteries. It is suggested that angina pectoris resulted from the inadequate circulatory response and is another clinical manifestation of the Shy-Drager syndrome.
R Silverberg; Y Naparstek; B S Lewis; M Levy
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  42     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1979 Oct 
Date Detail:
Created Date:  1980-02-15     Completed Date:  1980-02-15     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  910-3     Citation Subset:  IM    
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MeSH Terms
Angina Pectoris / complications*
Autonomic Nervous System*
Basal Ganglia Diseases / complications*
Coronary Circulation
Hypotension, Orthostatic / complications*,  physiopathology
Middle Aged
Nervous System Diseases / complications,  drug therapy,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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