Document Detail


Angina in thyrotoxicosis. Thyroid-related coronary artery spasm.
MedLine Citation:
PMID:  6402998     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ischemic heart disease is a common complication of thyrotoxicosis, although the exact mechanism has not been defined. A case is reported of angina and thyrotoxicosis in which the angina was reproduced by coronary artery spasm induced by ergonovine maleate, relieved by thyroid ablation, and reactivated by postablative thyroid replacement. Coronary arteriography did not show significant stenoses prior to ergonovine injection. Possible mechanisms of coronary artery spasm in thyrotoxicosis are briefly discussed. Hyperthyroidism should be considered as a cause of angina in any patient with rest pain and normal coronary arteries.
Authors:
H J Featherstone; D K Stewart
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of internal medicine     Volume:  143     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1983 Mar 
Date Detail:
Created Date:  1983-04-07     Completed Date:  1983-04-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  554-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Angina Pectoris / drug therapy,  etiology*
Angiography
Ergonovine / adverse effects
Humans
Hyperthyroidism / complications*,  drug therapy
Isosorbide Dinitrate / therapeutic use
Male
Middle Aged
Nitroglycerin / therapeutic use
Propranolol / therapeutic use
Thyroxine / therapeutic use*
Grant Support
ID/Acronym/Agency:
HL19451/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
525-66-6/Propranolol; 55-63-0/Nitroglycerin; 60-79-7/Ergonovine; 7488-70-2/Thyroxine; 87-33-2/Isosorbide Dinitrate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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