| Preview. Angelman syndrome: finding the lost arc. | |
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MedLine Citation:
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PMID: 20211128 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Angelman syndrome is a neurodevelopmental disorder caused by mutations in the maternally inherited UBE3A gene, which encodes a ubiquitin ligase. Greer et al. (2010) now identify a UBE3A substrate called Arc that promotes endocytosis of neuronal AMPA receptors, providing insight into synaptic defects that may underlie the cognitive deficits in Angelman syndrome. |
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Authors:
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Hwan-Ching Tai; Erin M Schuman |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Cell Volume: 140 ISSN: 1097-4172 ISO Abbreviation: Cell Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-09 Completed Date: 2010-03-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0413066 Medline TA: Cell Country: United States |
Other Details:
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Languages: eng Pagination: 608-10 Citation Subset: - |
Copyright Information:
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(c) 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Biology, Caltech, Pasadena, CA 91125, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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| Comments/Corrections | |
Comment On:
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Cell. 2010 Mar 5;140(5):704-16
[PMID:
20211139
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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