| Anesthetic, hypothermic, myorelaxant and anticonvulsant effects of synthetic eugenol derivatives and natural analogues. | |
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MedLine Citation:
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PMID: 7208593 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Nine newly synthesized eugenol derivatives were investigated in rats or mice as to their anesthetic, hypothermic, myorelaxant and anticonvulsant effects. Additional pharmacological activity which appeared during the experiments is described. For comparative purposes, six naturally occurring eugenol analogues were included in the study. The results are further discussed as to possible structure-activity relationships between the test compounds and the four investigated effects. |
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Authors:
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K Dallmeier; E A Carlini |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pharmacology Volume: 22 ISSN: 0031-7012 ISO Abbreviation: Pharmacology Publication Date: 1981 |
Date Detail:
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Created Date: 1981-05-26 Completed Date: 1981-05-26 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0152016 Medline TA: Pharmacology Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 113-27 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthetics Animals Anticonvulsants Body Temperature / drug effects Electroshock Eugenol / analogs & derivatives*, pharmacology Male Muscle Relaxants, Central Rats |
| Chemical | |
Reg. No./Substance:
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0/Anesthetics; 0/Anticonvulsants; 0/Muscle Relaxants, Central; 97-53-0/Eugenol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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