Document Detail

Anesthetic efficacy of a repeated intraosseous injection following a primary intraosseous injection.
MedLine Citation:
PMID:  18215666     Owner:  NLM     Status:  MEDLINE    
The purpose of this prospective, randomized, single-blinded study was to determine the anesthetic efficacy of a repeated intraosseous injection given 30 minutes after a primary intraosseous injection. Using a crossover design, 55 subjects randomly received a primary X-tip intraosseous injection (Dentsply Inc, York, PA) of 1.4 mL of 2% lidocaine with epinephrine (using the Wand; Milestone Scientific, Deerfield, IL) and a repeated intraosseous or mock injection at 30 minutes in two appointments. The first molar and adjacent teeth were pulp tested every 2 minutes for a total of 120 minutes. Success was defined as obtaining two consecutive 80 readings with the electric pulp tester. Success of the initial intraosseous injection was 100% for the first molar. The repeated intraosseous injection mimicked the initial intraosseous injection in terms of pulpal anesthesia and statistically provided another 15 minutes of pulpal anesthesia. In conclusion, using the methodology presented, repeating the intraosseous injection 30 minutes after an initial intraosseous injection will provide an additional 15 minutes of pulpal anesthesia.
Joanne Jensen; John Nusstein; Melissa Drum; Al Reader; Mike Beck
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2007-12-21
Journal Detail:
Title:  Journal of endodontics     Volume:  34     ISSN:  0099-2399     ISO Abbreviation:  J Endod     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-24     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7511484     Medline TA:  J Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  126-30     Citation Subset:  D    
Private Practice, Pleasant Hill, CA, USA.
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MeSH Terms
Anesthesia, Local / instrumentation
Anesthetics, Local / administration & dosage*
Bicuspid / drug effects
Cross-Over Studies
Dental Pulp / drug effects
Dental Pulp Test
Epinephrine / administration & dosage
Injections / instrumentation,  methods
Lidocaine / administration & dosage*
Molar / drug effects
Pain Measurement
Prospective Studies
Single-Blind Method
Time Factors
Vasoconstrictor Agents / administration & dosage
Reg. No./Substance:
0/Anesthetics, Local; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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