Document Detail


Anesthetic efficacy of 1.8 mL and 3.6 mL of 2% lidocaine with 1:100,000 epinephrine for maxillary infiltrations.
MedLine Citation:
PMID:  18215665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this prospective, randomized, single-blinded study was to measure the degree of anesthesia obtained with 1.8 mL and 3.6 mL of 2% lidocaine with 1:100,000 epinephrine in maxillary infiltrations. Ninety-six adult subjects randomly received infiltrations of 1.8 mL and 3.6 mL of the lidocaine solution at two separate appointments, in a crossover design. Thirty-two lateral incisors, 32 first premolars and 32 first molars were studied in this investigation. Anesthetic success (obtaining two consecutive 80 readings with the electric pulp tester) for the two volumes ranged from 97% to 100%. The onset of pulpal anesthesia was not statistically different between the two volumes. For both volumes, the lateral incisors had a higher percentage of anesthesia of short duration than the first premolar and first molar. The 3.6 mL volume provided a statistically longer duration of pulpal anesthesia for the lateral incisor, first premolar, and first molar.
Authors:
Alan Mikesell; Melissa Drum; Al Reader; Mike Beck
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Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of endodontics     Volume:  34     ISSN:  0099-2399     ISO Abbreviation:  J Endod     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-24     Completed Date:  2008-03-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7511484     Medline TA:  J Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  121-5     Citation Subset:  D    
Affiliation:
Private Practice; Wapakoneta, Ohio, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anesthetics, Local / administration & dosage*
Bicuspid / drug effects
Cross-Over Studies
Dental Pulp / drug effects
Dental Pulp Test
Electric Stimulation
Epinephrine / administration & dosage
Female
Humans
Incisor / drug effects
Injections
Lidocaine / administration & dosage*
Male
Maxilla / drug effects*
Molar / drug effects
Pain Measurement
Prospective Studies
Single-Blind Method
Time Factors
Vasoconstrictor Agents / administration & dosage
Chemical
Reg. No./Substance:
0/Anesthetics, Local; 0/Vasoconstrictor Agents; 137-58-6/Lidocaine; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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