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Anesthetic Efficacy of 1.8 mL versus 3.6 mL of 4% Articaine with 1:100,000 Epinephrine as a Primary Buccal Infiltration of the Mandibular First Molar.
MedLine Citation:
PMID:  21496653     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
INTRODUCTION: No study has compared 1.8 mL and 3.6 mL 4% articaine with 1:100,000 epinephrine in a mandibular buccal infiltration of the first molar. The authors conducted a prospective, randomized, single-blind, crossover study comparing the degree of pulpal anesthesia obtained with 1.8 mL and 3.6 mL 4% articaine with 1:100,000 epinephrine as a primary infiltration in the mandibular first molar.
METHODS: Eighty-six asymptomatic adult subjects randomly received a primary mandibular buccal first molar infiltration of 1.8 mL or 3.6 mL 4% articaine with 1:100,000 epinephrine in two separate appointments. The authors used an electric pulp tester to test the first molar for anesthesia in 3-minute cycles for 90 minutes after the injections.
RESULTS: Compared with the 1.8-mL volume of 4% articaine with 1:100,000 epinephrine, the 3.6-mL volume showed a statistically higher success rate (70% vs 50%).
CONCLUSIONS: The anesthetic efficacy of 3.6 mL 4% articaine with 1:100,000 epinephrine is better than 1.8 mL of the same anesthetic solution in a primary mandibular buccal infiltration of the first molar. However, the success rate of 70% is not high enough to support its use as a primary injection technique in the mandibular first molar.
Authors:
Matthew Martin; John Nusstein; Melissa Drum; Al Reader; Mike Beck
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Publication Detail:
Type:  Journal Article     Date:  2011-03-10
Journal Detail:
Title:  Journal of endodontics     Volume:  37     ISSN:  1878-3554     ISO Abbreviation:  J Endod     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7511484     Medline TA:  J Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  588-92     Citation Subset:  D    
Copyright Information:
Copyright © 2011 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Affiliation:
Private Practice, Richardson, Texas.
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