Document Detail


Anencephalus and drinking water composition.
MedLine Citation:
PMID:  324271     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The mortality rate (stillbirths and infant deaths) from anencephalus from 1950-1969 in 36 cities of over 50,000 population in Canada showed a negative association (r = -.39) with the concentration of magnesium in water sampled at domestic taps. The mortality rates showed negative associations with mean income and longitude, and a multiple regression model using the three factors showed significant effects of each and accounted for 69% of the intercity variation in rates. There were no significant associations seen with water calcium concentration or total hardness. Income, magnesium and longitude were also negatively associated with mortality rates from spina bifida, hydrocephalus, other congenital abnormalities, and total stillbirth and infant death rates, but the association with magnesium was significant only for total stillbirths. The negative association of anencephalus mortality and magnesium levels was also seen in a sample of 14 smaller towns in Ontario.
Authors:
J M Elwood
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of epidemiology     Volume:  105     ISSN:  0002-9262     ISO Abbreviation:  Am. J. Epidemiol.     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-06-30     Completed Date:  1977-06-30     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7910653     Medline TA:  Am J Epidemiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  460-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anencephaly / epidemiology,  etiology,  mortality*
Calcium / analysis
Canada
Congenital Abnormalities / mortality
Drinking
Female
Fetal Death / epidemiology
Fresh Water / analysis*
Humans
Hydrocephalus / mortality
Lithium / analysis
Magnesium / analysis
Pregnancy
Spinal Dysraphism / mortality
Water / analysis*
Water Softening
Water Supply
Chemical
Reg. No./Substance:
7439-93-2/Lithium; 7439-95-4/Magnesium; 7440-70-2/Calcium; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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