Document Detail


Anemia in hemodialysis patients.
MedLine Citation:
PMID:  836115     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The association between anemia and chronic renal failure has been recognized since the early 19th century. With the introduction of regular dialysis treatment, an understanding of all aspects of this uremic complication has become of great importance, including an appreciation of the hazards of multiple blood transfusions. This analysis of hemoglobin levels and transfusion requirements in 84 dialysis patients focuses specific attention on hemolytic mechanisms, blood loss, and the effect of bilateral nephrectomy on erythropoiesis. Because no replacement for renal erythropoietin is available, particular attention must be paid to less important, but partially correctable factors that contribute to anemia. Blood transfusion requirements can then be reduced to a minimum, together with the risks of hypersplenism, hepatitis, and sensitization of the patient to alloantigens.
Authors:
M R Higgins; M Grace; R A Ulan; D S Silverberg; K B Bettcher; J B Dossetor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  137     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1977 Feb 
Date Detail:
Created Date:  1977-03-31     Completed Date:  1977-03-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  172-6     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anemia, Hemolytic / etiology*,  therapy
Blood Transfusion
Erythropoietin / therapeutic use
Humans
Kidney Failure, Chronic / complications
Middle Aged
Nephrectomy
Renal Dialysis / adverse effects*
Chemical
Reg. No./Substance:
11096-26-7/Erythropoietin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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