Document Detail


Anemia in chronic congestive heart failure: frequency, prognosis, and treatment.
MedLine Citation:
PMID:  12808478     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Chronic heart failure (CHF) is a leading cause of morbidity and mortality. Although a precise definition for a cut-off value of hemoglobin level for anemia is still lacking, it has recently been found to be a common complication in CHF, occurring in 10-20% of patients. There are several possible pathogenetic mechanisms for anemia in CHF, and a precise underlying cause is found in only a minority of patients. In CHF, more than 50% of anemia cases are considered to be 'anemia in chronic illness'. In CHF patients, low hemoglobin values directly relate to poor peak oxygen consumption, disabling symptoms, and impaired survival. Recent pilot studies showed that correction of anemia with erythropoietin and iron may lead to improvement in symptoms and exercise capacity. These issues need to be tested in larger, double-blind, randomized, placebo-controlled trials before anemia treatment becomes routine in patients with CHF.
Authors:
Martino Crosato; Wolfram Steinborn; Stefan D Anker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Heart failure monitor     Volume:  4     ISSN:  1470-8590     ISO Abbreviation:  Heart Fail Monit     Publication Date:  2003  
Date Detail:
Created Date:  2003-06-16     Completed Date:  2003-11-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  101140283     Medline TA:  Heart Fail Monit     Country:  England    
Other Details:
Languages:  eng     Pagination:  2-6     Citation Subset:  IM    
Affiliation:
Imperial College, National Heart & Lung Institute, Department of Clinical Cardiology, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Anemia / complications*,  drug therapy,  epidemiology,  etiology
Erythropoietin / therapeutic use
Heart Failure / complications*
Hemoglobins / analysis
Humans
Iron / therapeutic use
Chemical
Reg. No./Substance:
0/Hemoglobins; 11096-26-7/Erythropoietin; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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