| Anemia after renal transplantation. | |
| | |
MedLine Citation:
|
PMID: 16997048 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Anemia in the setting of chronic kidney disease is a well-recognized phenomenon that is associated with decreasing renal function and deficiency of or resistance to erythropoietin. However, anemia in the post-renal transplantation setting has received comparatively less attention in the literature. In this review, we aim critically to appraise the available literature regarding posttransplantation anemia, concentrating in particular on the prevalence of posttransplantation anemia, its etiopathogenesis, potential effects on morbidity and mortality, and the rationale for intervention and treatment. Despite deficiencies in the literature, we conclude that posttransplantation anemia is a common phenomenon that can occur either early or late posttransplantation, and its causation is usually multifactorial and includes contributions notably from poor or decreasing renal function, immunosuppression, and iron deficiency. Conversely, there is a shortage of well-conducted prospective studies looking at the morbidity attributable to posttransplantation anemia and a lack of trial evidence to determine whether intervention improves patient morbidity and outcome. |
| | |
Authors:
|
Behdad Afzali; Salam Al-Khoury; Nilesh Shah; Ashraf Mikhail; Adrian Covic; David Goldsmith |
Related Documents
:
|
15673318 - Iron overload in kidney transplants: prospective analysis of biochemical and genetic ma... 2296348 - Development and progression of uremic changes in the mouse with surgically induced rena... 15300478 - Atypical relapse of hemolytic uremic syndrome after transplantation. 626068 - Cardiovascular impairment and physical working capacity in children with chronic renal ... 3102148 - Serial evaluation of lymphocyte function in bone marrow-grafted patients. 19793068 - Voriconazole is safe and effective as prophylaxis for early and late fungal infections ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: American journal of kidney diseases : the official journal of the National Kidney Foundation Volume: 48 ISSN: 1523-6838 ISO Abbreviation: Am. J. Kidney Dis. Publication Date: 2006 Oct |
Date Detail:
|
Created Date: 2006-09-25 Completed Date: 2006-10-12 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8110075 Medline TA: Am J Kidney Dis Country: United States |
Other Details:
|
Languages: eng Pagination: 519-36 Citation Subset: IM |
Affiliation:
|
Department of Nephrology and Transplantation, Guy's Hospital, London, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anemia, Iron-Deficiency
/
drug therapy,
epidemiology*,
etiology* Cardiovascular Diseases / physiopathology Erythropoiesis / drug effects, physiology Erythropoietin / blood, pharmacology, therapeutic use Erythropoietin, Recombinant / pharmacology, therapeutic use Humans Kidney Failure, Chronic / surgery Kidney Transplantation / adverse effects* Prevalence Risk Factors |
| Chemical | |
Reg. No./Substance:
|
0/Erythropoietin, Recombinant; 0/epoetin beta; 11096-26-7/Erythropoietin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Recurrent hyponatremia associated with citalopram and mirtazapine.
Next Document: The epidemiology of hemoglobin levels in patients with type 2 diabetes.