Document Detail

Androgen abuse and increased cardiac risk.
MedLine Citation:
PMID:  23211503     Owner:  NLM     Status:  MEDLINE    
The objectives of this article were to review the anabolic androgen steroids, specifically the direct and indirect effects on the cardiovascular system of the individuals who use them, and to summarize the evidence regarding the effects of androgens on the cardiovascular system. A search of the English-language scientific literature from 1976 to March 2012 was performed primarily by searching the MEDLINE and Embase databases and Google. Anabolic androgenic steroids are associated with direct effects such as cardiac muscle hypertrophy and myocardial fibrosis and indirect effects, including dyslipidemia, hypertension, arrhythmia, and myocardial infarction. It is likely that chronic exposure to these agents can result in significant alterations in the cardiovascular system, and their safety has not been fully established.
John P Higgins; Alireza Heshmat; Christopher L Higgins
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Southern medical journal     Volume:  105     ISSN:  1541-8243     ISO Abbreviation:  South. Med. J.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-05     Completed Date:  2013-02-11     Revised Date:  2013-05-15    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  670-4     Citation Subset:  AIM; IM    
Department of Internal Medicine, University of Texas Medical School at Houston, Houston, TX 77026, USA.
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MeSH Terms
Anabolic Agents / adverse effects*
Androgens / adverse effects*
Cardiovascular Diseases / chemically induced*
Risk Factors
Reg. No./Substance:
0/Anabolic Agents; 0/Androgens
Comment In:
South Med J. 2013 Apr;106(4):291   [PMID:  23558421 ]
South Med J. 2013 Apr;106(4):291-2   [PMID:  23558422 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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