Document Detail


Anatomy of a songbird basal ganglia circuit essential for vocal learning and plasticity.
MedLine Citation:
PMID:  19596062     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Vocal learning in songbirds requires an anatomically discrete and functionally dedicated circuit called the anterior forebrain pathway (AFP). The AFP is homologous to cortico-basal ganglia-thalamo-cortical loops in mammals. The basal ganglia portion of this pathway, Area X, shares many features characteristic of the mammalian striatum and pallidum, including cell types and connectivity. The AFP also deviates from mammalian basal ganglia circuits in fundamental ways. In addition, the microcircuitry, role of neuromodulators, and function of Area X are still unclear. Elucidating the mechanisms by which both mammalian-like and unique features of the AFP contribute to vocal learning may help lead to a broad understanding of the sensorimotor functions of basal ganglia circuits.
Authors:
Samuel D Gale; David J Perkel
Publication Detail:
Type:  Journal Article; Review     Date:  2009-07-22
Journal Detail:
Title:  Journal of chemical neuroanatomy     Volume:  39     ISSN:  1873-6300     ISO Abbreviation:  J. Chem. Neuroanat.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-15     Completed Date:  2010-05-04     Revised Date:  2011-09-26    
Medline Journal Info:
Nlm Unique ID:  8902615     Medline TA:  J Chem Neuroanat     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  124-31     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier B.V. All rights reserved.
Affiliation:
Graduate Program in Neurobiology and Behavior, University of Washington, Seattle, WA 98195-6515, United States.
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MeSH Terms
Descriptor/Qualifier:
Animals
Basal Ganglia / anatomy & histology,  cytology,  physiology*
Birds / physiology*
Brain / anatomy & histology,  physiology
Catecholamines / physiology
Globus Pallidus / anatomy & histology,  physiology
Learning / physiology*
Neural Pathways / anatomy & histology,  physiology
Neuronal Plasticity / physiology*
Neurons / physiology
Thalamus / cytology,  physiology
Vocalization, Animal / physiology*
Grant Support
ID/Acronym/Agency:
R01 MH066128-03/MH/NIMH NIH HHS; R01 MH066128-04/MH/NIMH NIH HHS; R01 MH066128-05/MH/NIMH NIH HHS; R01 MH066128-06A2/MH/NIMH NIH HHS; R56 MH066128-06/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Catecholamines
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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