Document Detail

Anatomical variations of pulmonary artery and associated cardiac defects in Tetralogy of Fallot.
MedLine Citation:
PMID:  19356333     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine pulmonary artery variations and other associated cardiac defects in patients with Tetralogy of Fallot (TOF). STUDY DESIGN: Cross-sectional, descriptive study. PLACE AND DURATION OF STUDY: The Children's Hospital and the Institute of Child Health, Lahore, from April 2006 to October 2007. METHODOLOGY: All patients with TOF, who underwent cardiac catheterization during this period, were included. Standard cine-angiograms were recorded and pulmonary artery sizing was done using z-scoring. RESULTS: A total of 216 patients with TOF were catheterized. Pulmonary Artery (PA) abnormalities were present in 84 (38.9%) patients. The commonest abnormality was isolated Left Pulmonary Artery (LPA) stenosis (n=27, 32.14%) followed by isolated hypoplasia of Main Pulmonary Artery (MPA) (n=18, 21.43%) and supra-valvular stenosis in (n=11, 13.1%) patients. LPA was absent in one patient, while 2 patients had both absent right and left PA with segmental branch pulmonary arteries originating directly from MPA. Associated cardiac lesions included right aortic arch in 34 (15%), additional muscular VSD vary in 13 (5.5%), Patent Ductus Arteriosus (PDA) in 11 (6%) and Major Aortopulmonary Collateral Arteries (MAPCA) in 2 (1.9%) patients. Significant coronary artery abnormality was present in 10 (4.6%) children. CONCLUSION: Pulmonary artery abnormalities were present in 38.9% of patients with TOF. Isolated LPA origin stenosis and MPA hypoplasia were the most common abnormalities. Significant associated cardiac lesions were present in one-third of the patients and included PDA, additional muscular VSD, coronary artery abnormalities and MAPCA.
Sadia Saeed; Syed Najam Hyder; Masood Sadiq
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  19     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-09     Completed Date:  2010-01-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  211-4     Citation Subset:  IM    
Department of Paediatric Cardiology, The Children's Hospital and Institute of Child Health, Lahore.
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MeSH Terms
Child, Preschool
Collateral Circulation
Cross-Sectional Studies
Ductus Arteriosus, Patent / complications,  pathology
Heart Catheterization*
Pulmonary Artery / abnormalities*,  pathology
Pulmonary Valve Stenosis / diagnosis*,  pathology
Tetralogy of Fallot / complications,  pathology*

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