Document Detail


Anatomical segregation of visual selection mechanisms in human parietal cortex.
MedLine Citation:
PMID:  23554503     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Visual selection requires mechanisms for representing object salience and for shifting the focus of processing to novel objects. It is not clear from computational or neural models whether these operations are performed within the same or different brain regions. Here, we use repetitive transcranial magnetic stimulation to briefly interfere with neural activity in individually localized regions of human posterior parietal cortex (PPC) that are putatively involved in attending to contralateral locations or shifting attention between locations. Stimulation over right ventral intraparietal sulcus impaired target discrimination at contralateral locations, whereas stimulation over right medial superior parietal lobule impaired target discrimination after a shift of attention regardless of its location. This double dissociation is consistent with neuroimaging studies and indicates that mechanisms of visual selection are partly anatomically segregated in human PPC.
Authors:
Paolo Capotosto; Annalisa Tosoni; Sara Spadone; Carlo Sestieri; Mauro Gianni Perrucci; Gian Luca Romani; Stefania Della Penna; Maurizio Corbetta
Related Documents :
24849363 - Heterosynaptic modulation of motor cortical plasticity in human.
21436523 - P300 audio-visual speller.
22378883 - Long-lasting plasticity of hippocampal adult-born neurons.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of neuroscience : the official journal of the Society for Neuroscience     Volume:  33     ISSN:  1529-2401     ISO Abbreviation:  J. Neurosci.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-04     Completed Date:  2013-05-28     Revised Date:  2013-10-17    
Medline Journal Info:
Nlm Unique ID:  8102140     Medline TA:  J Neurosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  6225-9     Citation Subset:  IM    
Affiliation:
Department of Neuroscience and Imaging and Institute of Advanced Biomedical Technologies, Gabriele D'Annunzio University, I-66110 Chieti, Italy. pcapotosto@unich.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Attention / physiology*
Choice Behavior / physiology*
Discrimination (Psychology) / physiology*
Female
Functional Laterality
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Male
Orientation / physiology
Oxygen / blood
Parietal Lobe / blood supply,  physiology*
Photic Stimulation
Transcranial Magnetic Stimulation
Young Adult
Grant Support
ID/Acronym/Agency:
R01 1R01MH096482/MH/NIMH NIH HHS; R01 MH096482/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
7782-44-7/Oxygen
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Dissociation between dorsal and ventral hippocampal theta oscillations during decision-making.
Next Document:  Functional characterization of the extraclassical receptive field in macaque V1: contrast, orientati...