| Anatomical accuracy of abdominal lesion localization. Retrospective automatic rigid image registration between FDG-PET and MRI. | |
| | |
MedLine Citation:
|
PMID: 21594303 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Software-based image registration can improve the diagnostic value of imaging procedures and is an alternative to hybrid scanners. The aim of this study was to evaluate the anatomical accuracy of automatic rigid image registration of independently acquired datasets of positron emission tomography with 18F-deoxyglucose and abdominal magnetic resonance imaging. Patients, methods: Analyses were performed on 28 abdominal lesions from 20 patients. The PET data were obtained using a stand-alone PET camera in 14 cases and a hybrid PET/CT scanner in 9 cases. The abdominal T1- and T2-weighted MRI scans were acquired on 1.5 T MRI scanners. The mean time interval between MRI and PET was 7.3 days (0-28 days). Automatic rigid registration was carried out using a self-developed registration tool integrated into commercial available software (InSpace for Siemens Syngo). Distances between the centres of gravity of 28 manually delineated neoplastic lesions represented in PET and MRI were measured in X-, Y-, and Z-direction. The intra- (intraclass correlation 0.94) and inter- (intraclass correlation 0.86) observer repeatability were high. Results: The average distance in all MRI sequences was 5.2±7.6 mm in X-direction, 4.0±3.7 mm in Y-direction and 6.1±5.1 mm in Z-direction. There was a significantly higher misalignment in Z-direction (p<0.05). The misalignment was not significantly different for the registration of T1- and T2- weighted sequences (p=0.7). Conclusion: The misalignment between FDG-PET and abdominal MRI registered using an automated rigid registration tool was comparable to data reported for software-based fusion between PET and CT. Although this imprecision may not affect diagnostic accuracy, it is not sufficient to allow for pixel-wise integration of MRI and PET information. |
| | |
Authors:
|
A Kiefer; T Kuwert; D Hahn; J Hornegger; M Uder; P Ritt |
Related Documents
:
|
10731893 - Juxtaacetabular ganglion as a differential diagnosis in pulsating groin masses. 19374493 - Intraneural ganglia in the hip and pelvic region. clinical article. 8312503 - Teaching high-resolution nuclear magnetic resonance to graduate students in biophysics. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-5-19 |
Journal Detail:
|
Title: Nuklearmedizin. Nuclear medicine Volume: 50 ISSN: 0029-5566 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
|
Created Date: 2011-5-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7609387 Medline TA: Nuklearmedizin Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Philipp Ritt, Clinic of Nuclear Medicine, University of Erlangen-Nürnberg, Krankenhausstr. 12, 91054 Erlangen, Germany, Tel. +49/(0)91 31/853 34 11, Fax +49/(0)91 31/853 92 62, E-mail: philipp.ritt@uk-erlangen.de. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A domino pericyclic route to polysubstituted salicylic acid derivatives: four sequential processes f...
Next Document: Metabolic tumour volume. Prognostic value in locally advanced squamous cell carcinoma of the head an...