Document Detail


Anatomic constraints for a total artificial heart in orthotopic heart transplant recipients.
MedLine Citation:
PMID:  8031808     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The anatomic constraints and design parameters for a heart prosthesis have not yet been defined in heart transplant recipients (i.e., the population most eligible for total artificial heart implantation). The parameters regarding anatomic constraints were measured in 26 consecutive patients undergoing orthotopic heart transplantation (median body surface area 1.9 m2) after cardiectomy. A full-sized contour model of the cylindric total artificial heart (diameter 97 mm; width 81 mm) was inserted into the pericardial cavity to decide the pump configuration and to verify its fit. The dimensions of this model were based on the miniature electromechanical total artificial heart that is currently under development. Fit was found to be adequate in most of the cases with no identifiable compression of adjacent vascular structures. The median intraoperative measurements that define pericardial constraints for a heart prosthesis were pericardial length (130 mm), width (160 mm), and depth (140 mm). We also took measurements from the excised hearts, which should provide a useful reference for other prosthetic devices. The current dimensions of our implantable total artificial heart were found acceptable for orthotopic implantation. Length of the pericardium and cardiothoracic ratio were identified as variables related to adequacy of fit.
Authors:
M Shiono; G P Noon; K R Hess; S Takatani; T Sasaki; Y Orime; J B Young; Y Nosé; M E DeBakey
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation     Volume:  13     ISSN:  1053-2498     ISO Abbreviation:  J. Heart Lung Transplant.     Publication Date:    1994 Mar-Apr
Date Detail:
Created Date:  1994-08-12     Completed Date:  1994-08-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9102703     Medline TA:  J Heart Lung Transplant     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  250-62     Citation Subset:  IM    
Affiliation:
Department of Surgery, Baylor College of Medicine, Houston, TX 77030.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anthropometry
Equipment Design
Female
Heart Failure / physiopathology,  surgery*
Heart Transplantation / physiology*
Heart, Artificial*
Hemodynamics / physiology
Humans
Male
Middle Aged
Models, Cardiovascular

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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