Document Detail

Anastomotic aneurysms after surgical treatment of Takayasu's arteritis: a 40-year experience.
MedLine Citation:
PMID:  9546229     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate the clinical characteristics of anastomotic aneurysms that develop in surgically treated patients with Takayasu's arteritis.
METHODS: Among 103 patients with Takayasu's arteritis treated surgically over 40 years, 91 patients with 259 anastomoses (allowing for exclusion of 12 operative deaths) participated in follow-up study from 1 month to 37.3 years with a mean value +/- SEM of 17.3 +/- 1.1 years with a follow-up completion rate of 93% at 30 years. The clinical characteristics of anastomotic aneurysms were clarified, and the influences of several factors (sites of anastomoses, occlusive or aneurysmal disease, suture material, preoperative systemic inflammation, and administration of corticosteroids) on formation of anastomotic aneurysms were analyzed by means of life-table method and Cox regression analysis.
RESULTS: Twenty-two uninfected anastomotic aneurysms were found among 14 patients (22 of 259 anastomoses, 8.5%). The interval between the previous operation and diagnosis varied from 1.6 to 30 years with a mean value +/- SEM of 9.8 +/- 1.8 years. The cumulative incidence of anastomotic aneurysm at 20 years was 12.0%. Systemic inflammation or steroid administration had little influence on formation of anastomotic aneurysm. Instead, anastomotic aneurysm tended to occur after operations for aneurysmal lesions.
CONCLUSIONS: Anastomotic aneurysm can occur anytime after operations for Takayasu's arteritis. The development of anastomotic aneurysm is not influenced by any factor specific to this disease except the presence of an aneurysmal lesion.
T Miyata; O Sato; J Deguchi; H Kimura; T Namba; K Kondo; M Makuuchi; C Hamada; A Takagi; Y Tada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of vascular surgery     Volume:  27     ISSN:  0741-5214     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-04-23     Completed Date:  1998-04-23     Revised Date:  2012-10-03    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  438-45     Citation Subset:  IM    
Second Department of Surgery, Faculty of Medicine, The University of Tokyo, Japan.
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MeSH Terms
Anastomosis, Surgical / adverse effects
Aneurysm, False / etiology*,  surgery
Aorta / surgery*
Follow-Up Studies
Life Tables
Middle Aged
Proportional Hazards Models
Retrospective Studies
Risk Factors
Takayasu Arteritis / surgery*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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