Document Detail

Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina.
MedLine Citation:
PMID:  16023538     Owner:  NLM     Status:  MEDLINE    
Metastatic involvement of the cerebro-spinal fluid (CSF) pathway in oligodendrogliomas is not uncommon; however, symptomatic involvement of the spinal cord is very rare: less of 10 cases have been published. To our knowledge, an intracranial oligodendroglioma presenting with symptoms of drop metastases in the cauda equina has never been reported. We report a case of 67-year-old woman who after 1 month of severe low back and legs pain developed symptoms of raised intracranial pressure. A spinal cord MRI showed multiple intradural nodular lesions at the level of the cauda equina, a MRI of the brain showed an intraventricular brain tumor. The histopathological diagnosis of both surgically treated lesions was anaplastic oligodendroglioma. The choices adopted in planning diagnostic and therapeutical procedures are discussed. The importance of the clinical and neuroradiological data in the diagnosis is stressed. Pathophysiology of the seeding of intracranial tumours via the cerebrospinal fluid is reviewed.
Massimo Natale; Pietro Spennato; Luciano Savarese; Antonio Bocchetti; Salvatore Esposito; Rosario Barbato
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  107     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-07-18     Completed Date:  2005-10-11     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  417-20     Citation Subset:  IM    
Department of Neurosurgery, Second University of Naples, c/o Ospedale CTO, Viale dei Colli Aminei 21, 80100, Naples, Italy.
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MeSH Terms
Cauda Equina*
Cerebral Ventricle Neoplasms / diagnosis,  pathology*,  therapy
Lateral Ventricles*
Lumbar Vertebrae
Middle Aged
Oligodendroglioma / diagnosis,  secondary*,  therapy
Peripheral Nervous System Neoplasms / diagnosis,  secondary*,  therapy

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