| Anaplastic large cell lymphoma presenting as acute liver failure: A report of two cases with review of literature. | |
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MedLine Citation:
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PMID: 21057166 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Primary hepatic anaplastic large cell lymphoma (ALCL) of the liver is a rare entity. We present here two cases of primary hepatic anaplastic large cell lymphoma (ALCL) of the null-cell type. Both the cases had jaundice with "B" symptoms and hepatomegaly. The serum billirubin and liver enzymes were raised in both cases. The liver showed sinusoidal infiltration by atypical lymphoid cells with marked nuclear pleomorphism, dispersed chromatin and prominent nucleoli in both the cases. These cells were positive for CD30, negative for CD3, CD20 and EMA, and diagnosed as ALCL of the null-cell type. We hereby report these cases with the review of literature on primary hepatic ALCLwith their possible etio-pathogenesis & diagnostic clues which may help in timely diagnosis & management in such cases. |
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Authors:
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Uma Nahar Saikia; Nidhi Sharma; Ajay Duseja; Ashish Bhalla; Kusum Joshi |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Annals of hepatology Volume: 9 ISSN: 1665-2681 ISO Abbreviation: Ann Hepatol Publication Date: 2010 Oct-Dec |
Date Detail:
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Created Date: 2010-11-08 Completed Date: 2011-02-17 Revised Date: 2012-04-05 |
Medline Journal Info:
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Nlm Unique ID: 101155885 Medline TA: Ann Hepatol Country: Mexico |
Other Details:
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Languages: eng Pagination: 457-61 Citation Subset: IM |
Affiliation:
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Departments of Histopathology, Hepatology and Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India. umasaikia@gmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antigens, CD30 / metabolism Bilirubin / blood Biopsy Diagnosis, Differential Fatal Outcome Female Humans Liver / enzymology, pathology Liver Failure, Acute / diagnosis*, metabolism, pathology Liver Neoplasms / diagnosis*, metabolism, pathology Lymphoma, Large-Cell, Anaplastic / diagnosis*, metabolism, pathology Male |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD30; 635-65-4/Bilirubin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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