Document Detail


Anaphylaxis to apple: is fasting a risk factor for LTP-allergic patients?
MedLine Citation:
PMID:  21114199     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Primary apple allergy is frequent in Mediterranean countries where hypersensitivity to lipid transfer protein (LTP) is common. Due to its stability upon pepsin digestion, LTP may cause systemic allergic reactions. This study investigated the potential risk associated with an isolated intake of apple while fasting in LTP-hypersensitive patients with clinical allergy to peach but not to apple.
PATIENTS AND METHODS: Based on the observation of 6 patients who experienced 7 apple-induced anaphylactic reactions that in 6 cases followed the ingestion of the fruit after fasting, open food challenges were carried out in 12 patients LTP-hypersensitive patients with peach allergy but tolerant to apple.
RESULTS: Four out of the 12 patients (33%) reacted to apple upon oral challenge.
CONCLUSION: Fasting seems to play a relevant role in the clinical expression of allergy to LTP. It is possible that in an empty gastrointestinal tract the allergen is absorbed more rapidly. Alternatively, pepsin might digest the food matrix more efficiently, thus increasing the concentration of the purified allergen that comes in contact with the gut mucosa.
Authors:
A Arena
Related Documents :
2661719 - Use of aquatic insects in determining submersion interval.
11927989 - Stability of species composition of fecal bifidobacteria in human subjects during ferme...
21196759 - Are ige levels to foods other than rosaceae predictive of allergy in lipid transfer pro...
21111099 - How is food insecurity associated with dietary behaviors? an analysis with low-income, ...
22079669 - Top-down control in a patchy environment: revisiting the stabilizing role of food-depen...
21430579 - Food insecurity and obesity in new york city primary care clinics.
16476179 - Composition, coagulation properties and parmigiano-reggiano cheese yield of italian bro...
9007419 - Why cardiac patients do not follow the nutritionist's advice: barriers in nutritional a...
22221919 - Studies on the genus mesodinium i: ultrastructure and description of mesodinium chamael...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European annals of allergy and clinical immunology     Volume:  42     ISSN:  1764-1489     ISO Abbreviation:  Eur Ann Allergy Clin Immunol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101466614     Medline TA:  Eur Ann Allergy Clin Immunol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  155-8     Citation Subset:  IM    
Affiliation:
Ambulatorio di Allergologia, Azienda Sanitaria Provinciale di Messina.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  GAPP Italy: "A survey on asthma on Italian physicians and patients".
Next Document:  Co-sensitisation (but co-recognition also) to novel banana and tomato allergens.