Document Detail

Anaphylaxis to Chlorhexidine-Coated Central Venous Catheters: A Case Series and Review of the Literature.
MedLine Citation:
PMID:  22568873     Owner:  NLM     Status:  Publisher    
Abstract Background: Anaphylactic reactions to chlorhexidine are rare but are being reported increasingly in association with a variety of products. Methods: We report three cases of anaphylaxis to chlorhexidine in patients presenting for cardiac surgery. Results: In each case, anaphylaxis was precipitated by the insertion of a central venous catheter impregnated with chlorhexidine acetate. Subsequent investigations confirmed chlorhexidine as the causal agent. Conclusion: Extensive use of chlorhexidine to reduce hospital-acquired infections has the potential to sensitize a small proportion of patients, leading to life-threatening anaphylaxis on subsequent exposure.
Achyut Guleri; Abhishek Kumar; Richard J M Morgan; Mike Hartley; David H Roberts
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-8
Journal Detail:
Title:  Surgical infections     Volume:  -     ISSN:  1557-8674     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815642     Medline TA:  Surg Infect (Larchmt)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1 Department of Clinical Microbiology, Blackpool Victoria Hospital , Blackpool, Lancashire, United Kingdom .
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