Document Detail

Anaphylaxis in labor secondary to prophylaxis against group B Streptococcus. A case report.
MedLine Citation:
PMID:  10319312     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Two strategies have been recommended by the Centers for Disease Control and Prevention and approved by the American College of Obstetrics and Gynecology to help prevent group B streptococcal disease in the newborn. Both involve using penicillin in labor. However, the potential for allergic and even anaphylactic reactions to penicillin exists. CASE: A patient was treated for risk factors for group B Streptococcus in labor and suffered a serious anaphylactic reaction to penicillin; it resulted in an emergency cesarean section. Although the patient and infant were eventually discharged, the patient developed disseminated intravascular coagulation and suffered acute tubular necrosis that required dialysis. CONCLUSION: Prophylaxis against group B streptococcal sepsis is of proven benefit, but the possible harm to the mother and fetus from treatment with penicillin must be recognized.
A B Dunn; J Blomquist; V Khouzami
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  44     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-06-29     Completed Date:  1999-06-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  381-4     Citation Subset:  IM    
Department of Obstetrics, Greater Baltimore Medical Center, Maryland 21204, USA.
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MeSH Terms
Anaphylaxis / chemically induced*,  therapy
Cesarean Section
Disseminated Intravascular Coagulation / chemically induced
Fetal Membranes, Premature Rupture / complications
Kidney Tubular Necrosis, Acute / chemically induced
Obstetric Labor Complications / drug therapy*,  etiology
Obstetric Labor, Premature / complications
Penicillins / adverse effects*
Practice Guidelines as Topic
Risk Factors
Streptococcal Infections / drug therapy*,  etiology
Streptococcus agalactiae*
Reg. No./Substance:

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