Document Detail

Anaphylaxis from medroxyprogesterone acetate.
MedLine Citation:
PMID:  15121602     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: More than 30 million women in more than 90 countries use depot medroxyprogesterone acetate as an injectable contraceptive agent, and it is thought to be very safe. However, it should be recognized that serious and potentially life-threatening adverse effects can occur. CASE: A 40-year-old para 2 went into anaphylactic shock after receiving 150 mg of depot medroxyprogesterone acetate intramuscularly. She was not taking any other medication, and there was no history of allergy to food or cosmetics. She responded fully to immediate resuscitation. A repeat episode occurred when she received another dose 12 weeks later. CONCLUSION: Although thought to be very safe, life-threatening adverse effects can occur with depot medroxyprogesterone acetate, and practitioners should be prepared for such eventuality.
Daniel O Selo-Ojeme; Amna Tillisi; Christopher C Welch
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  103     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-05-03     Completed Date:  2004-06-04     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1045-6     Citation Subset:  AIM; IM    
Directorate of Paediatrics, Obstetrics and Gynaecology, Basildon and Thurrock University Hospitals NHS Trust, Nethermayne, Basildon, England.
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MeSH Terms
Anaphylaxis / etiology*,  therapy
Contraceptive Agents, Female / administration & dosage,  adverse effects*
Injections, Intramuscular
Medroxyprogesterone Acetate / administration & dosage,  adverse effects*
Reg. No./Substance:
0/Contraceptive Agents, Female; 71-58-9/Medroxyprogesterone Acetate

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