| Anaphylactoid syndrome of pregnancy after intracervical dinoprostone for cervical ripening: a report of 3 cases. | |
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MedLine Citation:
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PMID: 15841940 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Three cases of anaphylactoid syndrome of pregnancy developed in association with the use of intracervical dinoprostone for cervical ripening. CASES: All cases occurred at our institution between October 1996 and February 2001. The patients developed respiratory symptoms shortly after placement of 0.25 mg of intracervical dinoprostone gel. Hemodynamic changes, manifested by tetanic uterine contractions and fetal heart rate decelerations, followed. Subsequently all 3 patients developed disseminated intravascular coagulation, characterized by severe hypofibrinogenemia. CONCLUSION: There appears to be an association between intracervical dinoprostone for cervical ripening and anaphylactoid syndrome of pregnancy. Clinicians utilizing this route of dinoprostone administration should be familiar with this rare but potentially life-threatening complication. |
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Authors:
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William Cusick; Domenico Leuci; Richard R Viscarello; John F Rodis |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of reproductive medicine Volume: 50 ISSN: 0024-7758 ISO Abbreviation: J Reprod Med Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-04-21 Completed Date: 2005-07-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0173343 Medline TA: J Reprod Med Country: United States |
Other Details:
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Languages: eng Pagination: 225-8 Citation Subset: IM |
Affiliation:
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Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Stamford Hospital, Stamford, Connecticut 06904, USA. wcusick@stamhealth.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Topical Adult Anaphylaxis / chemically induced* Cervical Ripening / drug effects* Dinoprostone / administration & dosage, adverse effects*, therapeutic use* Disseminated Intravascular Coagulation / etiology* Female Heart Rate, Fetal Humans Middle Aged Oxytocics / administration & dosage, adverse effects*, therapeutic use* Pregnancy Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Oxytocics; 363-24-6/Dinoprostone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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