Document Detail


Anaphylactoid reactions to radiocontrast agents: prevention and treatment in the cardiac catheterization laboratory.
MedLine Citation:
PMID:  19805846     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The use of iodinated contrast agents for angiography dates back to the 1920s. The initial prototype has undergone modifications to reduce the toxicity and discomfort associated with the early contrast molecules. More importantly, these changes have dramatically decreased the rate and risk for severe adverse reactions such as hypersensitivity and anaphylaxis. With over 15 million contrast-requiring procedures performed annually in the United States, it is important to understand the risk factors, pathogenesis, diagnosis, prevention and treatment of contrast-induced anaphylactoid reactions. Reviews of adverse reactions are sparse in the cardiology literature, except for a landmark review in 1995 by Goss et al, which has served as the only practice guideline to date for cardiologists. In this report, we review the most recent literature to provide a guide for the general and interventional cardiologist in regards to the pretreatment and management of contrast-related reactions specifically in the cardiac catheterization laboratory.
Authors:
Keshav R Nayak; Andrew A White; Jeffrey J Cavendish; Colin M Barker; David E Kandzari
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  21     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-06     Completed Date:  2010-02-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  548-51     Citation Subset:  IM    
Affiliation:
Interventional Cardiology, Division of Cardiovascular Diseases, Scripps Clinic Torrey Pines, 10666 N. Torrey Pines Road, S1056, La Jolla, CA 92037, USA. Nayak.keshav@scrippshealth.org
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MeSH Terms
Descriptor/Qualifier:
Anaphylaxis / chemically induced,  prevention & control*
Contrast Media / adverse effects*
Epinephrine / therapeutic use
Heart Catheterization / adverse effects*,  methods
Histamine Antagonists / therapeutic use
Humans
Steroids / therapeutic use
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Histamine Antagonists; 0/Steroids; 51-43-4/Epinephrine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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