| Anaphylactoid and anaphylactic reactions. Hazards of beta-blockers. | |
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MedLine Citation:
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PMID: 7669259 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies have demonstrated greater hazards associated with anaphylaxis in patients receiving beta-blockers. Serious anaphylaxis is more frequent. Evidence suggests this occurs via modulation of adenylate cyclase, which can influence release of anaphylactogenic mediators. Treatment of anaphylaxis in patients exposed to beta-blockers is complicated because therapeutic administration of epinephrine (adrenaline) may be ineffective or promote undesired alpha-adrenergic and vagotonic effects. Risk reduction efforts should be considered for patients receiving beta-blockers who are prone to experience anaphylaxis. |
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Authors:
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D M Lang |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Drug safety : an international journal of medical toxicology and drug experience Volume: 12 ISSN: 0114-5916 ISO Abbreviation: Drug Saf Publication Date: 1995 May |
Date Detail:
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Created Date: 1995-10-19 Completed Date: 1995-10-19 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9002928 Medline TA: Drug Saf Country: NEW ZEALAND |
Other Details:
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Languages: eng Pagination: 299-304 Citation Subset: IM |
Affiliation:
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Department of Medicine, Hahnemann University Hospital, Philadelphia, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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adverse effects*,
pharmacokinetics Anaphylaxis / chemically induced* Humans |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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