Document Detail


Anaphase progression and furrow establishment in nocodazole-arrested PtK1 cells.
MedLine Citation:
PMID:  7273957     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship between progression through anaphase and furrow establishment was investigated in PtK1 cells using the anti-mitotic agent Nocodazole to arrest cells at different points in anaphase. The capacity of cells to furrow was compared to the kinetochore-kinetochore separation attained at the time of arrest. For the stages of anaphase examined, furrowing capacity increased directly with kinetochore-kinetochore separation until complete furrows were formed after kinetochore-kinetochore separations of 14 micron or more were reached. Furrow establishment thus occurs during a definite interval during anaphase in PtK1 cells. Results from electron microscopy of both Nocodazole-treated and control cells suggest that a population of astral microtubules may be important for furrow establishment.
Authors:
J M Mullins; J A Snyder
Related Documents :
1993737 - Immunolocalization and molecular properties of a high molecular weight microtubule-bund...
22145477 - Congenital hypothyroidism in association with chromosome 3p25.3-pter deletion.
21621767 - A family with xq22.3q25 interstitial deletion and normal ovarian function.
17673597 - The internervous safe zone for incision of the capsule of the hip. a cadaver study.
10780787 - Mechanism of spreading of the highly related neurofibromatosis type 1 (nf1) pseudogenes...
7504987 - The human gene for water channel aquaporin 1 (aqp1) is localized on chromosome 7p15-->p14.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Chromosoma     Volume:  83     ISSN:  0009-5915     ISO Abbreviation:  Chromosoma     Publication Date:  1981  
Date Detail:
Created Date:  1981-11-22     Completed Date:  1981-11-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  2985138R     Medline TA:  Chromosoma     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  493-505     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anaphase / drug effects*
Animals
Benzimidazoles / pharmacology*
Carbamates / pharmacology*
Cell Line
Chromosomes / ultrastructure
Kidney
Marsupialia
Microscopy, Electron
Nocodazole
Grant Support
ID/Acronym/Agency:
GM26802/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Benzimidazoles; 0/Carbamates; 31430-18-9/Nocodazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Macronuclear chromatin organization in Paramecium primaurelia.
Next Document:  Arrangement of prematurely condensed chromosomes in cultured cells and lymphocytes of the Indian mun...