Document Detail


Analyzing threshold pressure limitations in microfluidic transistors for self-regulated microfluidic circuits.
MedLine Citation:
PMID:  23284181     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This paper reveals a critical limitation in the electro-hydraulic analogy between a microfluidic membrane-valve (μMV) and an electronic transistor. Unlike typical transistors that have similar on and off threshold voltages, in hydraulic μMVs, the threshold pressures for opening and closing are significantly different and can change, even for the same μMVs depending on overall circuit design and operation conditions. We explain, in particular, how the negative values of the closing threshold pressures significantly constrain operation of even simple hydraulic μMV circuits such as autonomously switching two-valve microfluidic oscillators. These understandings have significant implications in designing self-regulated microfluidic devices.
Authors:
Sung-Jin Kim; Ryuji Yokokawa; Shuichi Takayama
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-07
Journal Detail:
Title:  Applied physics letters     Volume:  101     ISSN:  0003-6951     ISO Abbreviation:  Appl Phys Lett     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-1-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9881183     Medline TA:  Appl Phys Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  234107     Citation Subset:  -    
Affiliation:
Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.
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