Document Detail


Analytical studies on two amino acid derivatives of anticonvulsant activity.
MedLine Citation:
PMID:  12403296     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Qualitative and quantitative methods of analysis of two new amino acid derivatives, potential anticonvulsants of low neurotoxicity: N-acetyl-gamma-aminobutyric acid benzylamide (1) and N-melhyl-gamma-aminobutyric acid benzylamide (2) were developed. Qualitative analysis includes characteristic colour reactions, chromatographic (TLC) investigations, IR and UV spectra interpretation and quantitative analysis involves spectrophotometric, chromatographic (HPLC). acidimetric and argentomeric methods.
Authors:
Elzbieta Pirianowicz-Chaber; Ryszard Paruszewski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta poloniae pharmaceutica     Volume:  59     ISSN:  0001-6837     ISO Abbreviation:  Acta Pol Pharm     Publication Date:    2002 Jul-Aug
Date Detail:
Created Date:  2002-10-29     Completed Date:  2002-12-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985167R     Medline TA:  Acta Pol Pharm     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  239-41     Citation Subset:  IM    
Affiliation:
Department of Drug Chemistry, The Medical University of Warsaw, Poland.
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MeSH Terms
Descriptor/Qualifier:
Amino Acids / analysis*,  chemistry
Anticonvulsants / analysis*,  chemistry
Chromatography, High Pressure Liquid / methods,  statistics & numerical data
gamma-Aminobutyric Acid / analysis,  chemistry
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Anticonvulsants; 56-12-2/gamma-Aminobutyric Acid

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