Document Detail

Analytical problems with putrefaction in a fatal case involving ergotamine and pentazocine.
MedLine Citation:
PMID:  617989     Owner:  NLM     Status:  MEDLINE    
A 29-year-old male drug addict was found dead at the bottom of a staircase. Analysis of the acid-hydrolized blood showed the presence of pentazocine and two characteristic compounds that contained L-phenylalanine and D-proline, linked together by peptide bounds. It was shown that the latter two components could emanate from the peptide part of ergotamine under the conditions used. It seemed likely that, at the time of analysis, pentazocine and ergotamine were present at concentrations far above therapeutic values. A third component in the blood could not be identified.
R A de Zeeuw; F J van Mansvelt; J E Greving
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of forensic sciences     Volume:  22     ISSN:  0022-1198     ISO Abbreviation:  J. Forensic Sci.     Publication Date:  1977 Jul 
Date Detail:
Created Date:  1979-05-16     Completed Date:  1979-05-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375370     Medline TA:  J Forensic Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  550-7     Citation Subset:  IM    
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MeSH Terms
Chromatography, Gas
Chromatography, Thin Layer
Ergotamine / blood*
Forensic Medicine
Gas Chromatography-Mass Spectrometry
Lactams / blood
Mass Spectrometry
Pentazocine / blood*
Postmortem Changes*
Reg. No./Substance:
0/Lactams; 113-15-5/Ergotamine; 359-83-1/Pentazocine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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