Document Detail

Analytical Specificity and Sensitivity of the APTIMA Combo 2 and APTIMA GC Assays for Detection of Commensal Neisseria Species and Neisseria gonorrhoeae on the Gen-Probe Panther Instrument.
MedLine Citation:
PMID:  23324980     Owner:  NLM     Status:  In-Data-Review    
ABSTRACT: Genetic detection of Neisseria gonorrhoeae is replacing culture for increased diagnostic sensitivity. Specificity of several nucleic acid amplification tests is suboptimal. Herein, the Gen-Probe APTIMA Combo 2 and APTIMA GC assays had 100% specificity and 100% sensitivity after confirmatory testing, when testing 298 isolates of nongonococcal Neisseria and related species and 205 gonococcal isolates.
Daniel Golparian; Sepehr N Tabrizi; Magnus Unemo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Sexually transmitted diseases     Volume:  40     ISSN:  1537-4521     ISO Abbreviation:  Sex Transm Dis     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705941     Medline TA:  Sex Transm Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  175-8     Citation Subset:  IM    
From the *WHO Collaborating Centre for Gonorrhoea and Other STIs, National Reference Laboratory for Pathogenic Neisseria, Örebro, Sweden; †Department of Laboratory Medicine, Clinical Microbiology, Örebro University Hospital, Örebro, Sweden; and ‡Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia.
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