| Analytic assessment under ultraviolet light of actinic lentigines under bleaching treatment. | |
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MedLine Citation:
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PMID: 21649815 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background Actinic (solar) lentigines are melanotic tumors frequently developed during photoaging on the dorsum of the hands. Bleaching (whitening) agents are commonly offered to fade their darker aspect. In general, regular colorimetric methods show poor sensitivity to disclose any bleaching effect. Method The present randomized controlled study on 24 women was designed to objectively assess the clinical efficacy of a combination of bleaching agents on actinic lentigines. In the endeavor of improving sensitivity, the ultraviolet light-enhanced visualization (ULEV) method was used to derive analytical measurements of lentigo areas and darkness. The test product was a commercially available formulation associating glycolic acid, kojic acid, lipohydroxyacid, and a Vitreoscilla extract. The Analysis(®) Olympus and Adobe Photoshop(®) quantitative methods were applied to the ULEV pictures. Results Data indicated a rapid bleaching effect arising as early as after 1 month of daily applications. The effect progressively increased over 3 months of therapy. Conclusion The presently described analytical method appears to be sensitive to document some bleaching effects on actinic lentigines. |
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Authors:
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Gérald E Piérard; Sophie Seité; André Rougier; Pascale Quatresooz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of cosmetic dermatology Volume: 10 ISSN: 1473-2165 ISO Abbreviation: J Cosmet Dermatol Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101130964 Medline TA: J Cosmet Dermatol Country: England |
Other Details:
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Languages: eng Pagination: 104-9 Citation Subset: IM |
Copyright Information:
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© 2011 Wiley Periodicals, Inc. |
Affiliation:
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Laboratory of Skin Bioengineering and Imaging, Department of Dermatopathology, University Hospital of Liège, Liège, Belgium La Roche-Posay Pharmaceutical Laboratories, Asnières, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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