Document Detail

Analysis of viscoelastic wall properties in ovine arteries.
MedLine Citation:
PMID:  19272946     Owner:  NLM     Status:  MEDLINE    
In this paper, we analyze how elastic and viscoelastic properties differ across seven locations along the large arteries in 11 sheep. We employ a two-parameter elastic model and a four-parameter Kelvin viscoelastic model to analyze experimental measurements of vessel diameter and blood pressure obtained in vitro at conditions mimicking in vivo dynamics. Elastic and viscoelastic wall properties were assessed via solutions to the associated inverse problem. We use sensitivity analysis to rank the model parameters from the most to the least sensitive, as well as to compute standard errors and confidence intervals. Results reveal that elastic properties in both models (including Young's modulus and the viscoelastic relaxation parameters) vary across locations (smaller arteries are stiffer than larger arteries). We also show that for all locations, the inclusion of viscoelastic behavior is important to capture pressure-area dynamics.
Daniela Valdez-Jasso; Mansoor A Haider; H T Banks; Daniel Bia Santana; Yanina Zócalo Germán; Ricardo L Armentano; Mette S Olufsen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2008-08-15
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  56     ISSN:  1558-2531     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-04-03     Completed Date:  2009-09-02     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  210-9     Citation Subset:  IM    
Department of Mathematics, North Carolina State University, Raleigh, NC 27695 USA.
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MeSH Terms
Arteries / physiology*
Biomechanics / physiology*
Blood Pressure
Equipment Design
Models, Cardiovascular*
Nonlinear Dynamics
Sensitivity and Specificity
Signal Processing, Computer-Assisted*

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