| Analysis of upper airway obstruction by sleep videofluoroscopy in obstructive sleep apnea: A Large Population-Based Study. | |
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MedLine Citation:
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PMID: 21919011 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVES/HYPOTHESIS: To analyze the pattern of the upper airway obstruction in a large cohort of obstructive sleep apnea (OSA) patients using sleep videofluoroscopy (SVF). STUDY DESIGN: Retrospective analysis. METHODS: This study included 922 OSA patients who underwent both polysomnography and SVF. Their mean age, apnea-hypopnea index, and body mass index were 46.8 years, 34.2 per hour, and 26.2 kg/m(2) , respectively. Sleep was induced by intravenous injection of midazolam, and the obstruction pattern was determined on SVF when oxygen saturation dropped by more than 4% in pulse oxymetry. RESULTS: The anatomic structure and airway level, which were most commonly involved in obstruction, were the soft palate (77.9%) and the oropharynx (88.1%), respectively. The soft palate alone was the most common obstructed structure in mild OSA (43.2%), and the combination of the soft palate and the tongue base was more frequent in severe OSA (45.2%). The tongue base or the hypopharynx was progressively more involved in moderate/severe OSA cases (P < .001, respectively), and a multiplicity of obstruction pattern also increased according to OSA severity (P < .001). However, 32.4% of the patients with mild OSA also had multiple obstructive anatomic structures. CONCLUSIONS: Even if multiplicity of obstruction pattern was most commonly associated with severe OSA, almost one third of mild OSA patients also showed multiple anatomic structures and levels of obstruction. Therefore, a precise evaluation for multiplicity of obstruction patterns should precede the decision of a treatment plan, regardless of disease severity. |
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Authors:
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Chul Hee Lee; Sung-Lyong Hong; Chae-Seo Rhee; Sang-Wook Kim; Jeong-Whun Kim |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-14 |
Journal Detail:
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Title: The Laryngoscope Volume: - ISSN: 1531-4995 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607378 Medline TA: Laryngoscope Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc. |
Affiliation:
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Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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