Document Detail


Analysis of transient otoacoustic emissions and brainstem evoked auditory potentials in neonates with hyperbilirubinemia.
MedLine Citation:
PMID:  19649489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyperbilirubinemia is toxic to the auditory pathways and to the central nervous system, leaving sequelae such as hearing loss and encephalopathy. AIM: to assess the hearing of neonates with hyperbilirubinemia, using transient evoked otoacoustic emissions (TOAEs) and brainstem evoked auditory potentials (BEAP). Prospective study. MATERIALS AND METHODS: we had two groups: GI (n-25), neonates with hyperbilirubinemia; GII (n-22), neonates without hyperbilirubinemia and without risk factors for hearing loss. All the neonates had up to 60 days of life and were submitted to TOAE and BEAP. RESULTS: 12 neonates from GI and 10 from GII were girls and 13 from GI and 12 from GII were boys. TOAEs were present in all the children, however with lower amplitudes in GI, especially in the frequencies of 2 and 3KHz (p < 0.05). Regarding the BEAP, we observed a mild PV and LI-V increase in BI. The alterations observed in these tests do not correlate to the serum levels of bilirubin. CONCLUSIONS: in neonates with hyperbilirubinemia, we noticed lower TOAE amplitudes and mild PV and LI-V increase, indicating cochlear and retrocochlear disorders, stressing the importance of using both tests and carefully reading them in these evaluations.
Authors:
Daniela Polo Camargo da Silva; Regina Helena Garcia Martins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brazilian journal of otorhinolaryngology     Volume:  75     ISSN:  1808-8686     ISO Abbreviation:  Braz J Otorhinolaryngol     Publication Date:    2009 May-Jun
Date Detail:
Created Date:  2009-08-03     Completed Date:  2010-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101207337     Medline TA:  Braz J Otorhinolaryngol     Country:  Brazil    
Other Details:
Languages:  eng; por     Pagination:  381-6     Citation Subset:  IM    
Affiliation:
Bases Gerais da Cirurgia program, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista. daniela-polo@fmb.unesp.br
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MeSH Terms
Descriptor/Qualifier:
Case-Control Studies
Evoked Potentials, Auditory, Brain Stem / physiology*
Female
Hearing Loss, Sensorineural / diagnosis,  etiology*,  physiopathology
Humans
Hyperbilirubinemia, Neonatal / complications*
Infant, Newborn
Male
Neonatal Screening
Otoacoustic Emissions, Spontaneous / physiology*
Prospective Studies

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