| Analysis of time reduction methods for magnetic resonance elastography of the brain. | |
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MedLine Citation:
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PMID: 20817440 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Magnetic resonance elastography (MRE) uses a phase-contrast MRI technique to image shear wave propagation in tissue followed by the mathematical inversion of the equations of motion governing tissue mechanics to noninvasively image tissue stiffness. This work investigates the impact of various MR sampling strategies designed to reduce acquisition times on the accuracy of MRE inversions. The results indicate that brain MRE data can be significantly truncated while maintaining a mean global stiffness error less than 10%. The results also indicate that brain MRE data can be collected in as few as eight lines of k-space. This degree of data truncation is possible due to the relatively low spatial frequency content and low amplitude of the shear waves observed during brain MRE exams and will facilitate the design of rapid brain MRE protocols for future clinical investigations. |
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Authors:
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Matthew C Murphy; Kevin J Glaser; Armando Manduca; Joel P Felmlee; Jon Huston; Richard L Ehman |
Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Magnetic resonance imaging Volume: 28 ISSN: 1873-5894 ISO Abbreviation: Magn Reson Imaging Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-22 Completed Date: 2011-03-30 Revised Date: 2011-12-21 |
Medline Journal Info:
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Nlm Unique ID: 8214883 Medline TA: Magn Reson Imaging Country: Netherlands |
Other Details:
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Languages: eng Pagination: 1514-24 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Mayo Clinic, Department of Radiology, Rochester, MN 55905, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Algorithms* Brain / anatomy & histology*, physiology* Elastic Modulus / physiology Elasticity Imaging Techniques / methods* Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods* Reproducibility of Results Sensitivity and Specificity |
| Grant Support | |
ID/Acronym/Agency:
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EB001981/EB/NIBIB NIH HHS; R01 EB001981-10/EB/NIBIB NIH HHS; R01 EB001981-12/EB/NIBIB NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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