Analysis of the third and fourth cell cycles of mouse early development. | |
MedLine Citation:
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PMID: 3944805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The third (4-cell) and fourth (8-cell) cell cycles of early mouse development have been analysed in populations of blastomeres synchronized to the preceding cleavage division. DNA content was measured microdensitometrically. The entry of blastomeres into these cell cycles showed considerable heterogeneity both within and between individual embryos. This heterogeneity was greater in the fourth than in the third cell cycle. The component phases of the third cell cycle were estimated as G1 = 1 h, S = 7 h, and G2 + M = 2-5 h, and those of the fourth cell cycle as G1 = 2 h, S = 7 h, and G2 + M = 1-3 h. |
Authors:
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R K Smith; M H Johnson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of reproduction and fertility Volume: 76 ISSN: 0022-4251 ISO Abbreviation: J. Reprod. Fertil. Publication Date: 1986 Jan |
Date Detail:
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Created Date: 1986-03-07 Completed Date: 1986-03-07 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376367 Medline TA: J Reprod Fertil Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 393-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
MeSH Terms | |
Descriptor/Qualifier:
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Animals Blastomeres / cytology* Cell Cycle DNA / biosynthesis Embryo, Mammalian / metabolism Embryonic and Fetal Development Female Mice Mice, Inbred Strains Time Factors |
Chemical | |
Reg. No./Substance:
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9007-49-2/DNA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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