Document Detail

Analysis of the third and fourth cell cycles of mouse early development.
MedLine Citation:
PMID:  3944805     Owner:  NLM     Status:  MEDLINE    
The third (4-cell) and fourth (8-cell) cell cycles of early mouse development have been analysed in populations of blastomeres synchronized to the preceding cleavage division. DNA content was measured microdensitometrically. The entry of blastomeres into these cell cycles showed considerable heterogeneity both within and between individual embryos. This heterogeneity was greater in the fourth than in the third cell cycle. The component phases of the third cell cycle were estimated as G1 = 1 h, S = 7 h, and G2 + M = 2-5 h, and those of the fourth cell cycle as G1 = 2 h, S = 7 h, and G2 + M = 1-3 h.
R K Smith; M H Johnson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  76     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-03-07     Completed Date:  1986-03-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  393-9     Citation Subset:  IM    
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MeSH Terms
Blastomeres / cytology*
Cell Cycle
DNA / biosynthesis
Embryo, Mammalian / metabolism
Embryonic and Fetal Development
Mice, Inbred Strains
Time Factors
Reg. No./Substance:

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