| Analysis of temporal artery biopsies in an 18-year period at a community hospital. | |
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MedLine Citation:
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PMID: 19712860 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To identify analytical and clinical variables that may improve the effectiveness of temporal artery biopsy (TAB) for the diagnosis of giant cell arteritis (GCA). MATERIALS AND METHODS: A retrospective study of TABs conducted between 1989 and 2007 at the 450-bed Hospital Parc Taul?, Sabadell. Demographic data, clinical manifestations, analytical data prior to the biopsy and final diagnoses were recorded, including only those cases in which these data were reflected in the clinical history. RESULTS: In this period, 278 TABs were conducted in 181 women (65.1%) and 97 men (mean age 74 years). Seventy-nine (28.4%) were positive (GCA+) and 199 (71.5%) negative (TAB-). The most frequent final diagnoses in the TAB- group were: polymyalgia rheumatica (PMR) (18.6%), giant cell arteritis plus negative TAB (GCA-) (13.6%), tension headache (7.5%), infection (7.5%), other vasculitis (7.5%), and neoplasm (6.0%). The GCA+ group was compared with the TAB- group, the GCA- group and the PMR group. In the multivariate analysis only headache (RR 3.6), jaw claudication (RR 2.9) and abnormal temporal artery on palpation (RR 2.5) revealed statistical differences between the GCA+ and TAB- groups. CONCLUSION: One third of the biopsies performed at our centre were positive for GCA. The clinical variables that best predicted a positive TAB in our series were headache, jaw claudication, and abnormal temporal artery on palpation. |
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Authors:
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B Mar?; M Monteagudo; E Bustamante; J P?rez; A Casanovas; R Jordana; C Tolosa; J Oristrell |
Publication Detail:
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Type: Journal Article Date: 2009-06-03 |
Journal Detail:
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Title: European journal of internal medicine Volume: 20 ISSN: 1879-0828 ISO Abbreviation: Eur. J. Intern. Med. Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-28 Completed Date: 2010-01-26 Revised Date: 2010-02-11 |
Medline Journal Info:
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Nlm Unique ID: 9003220 Medline TA: Eur J Intern Med Country: Netherlands |
Other Details:
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Languages: eng Pagination: 533-6 Citation Subset: IM |
Copyright Information:
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2009 European Federation of Internal Medicine. |
Affiliation:
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Internal Medicine Service, Hospital de Sabadell, Fundaci? Parc Tauli-Institut Universitari (UAB), 08208 Sabadell, Barcelona, Spain. Bmari@tauli.cat |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Biopsy* Cohort Studies Diagnosis, Differential Female Giant Cell Arteritis / complications, pathology* Hospitals, Community Humans Male Middle Aged Polymyalgia Rheumatica / diagnosis Predictive Value of Tests Retrospective Studies Risk Factors Spain Temporal Arteries / pathology* |
| Comments/Corrections | |
Comment In:
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Eur J Intern Med. 2010 Feb;21(1):51
[PMID:
20122617
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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